Scindy Pharmaceutical’s next-generation in vivo lipid nanoparticle technology integrates cutting-edge targeted delivery strategies while building on traditional delivery methods. Our In vivo NeoLNP™ technology enhances the accuracy and efficiency of RNA delivery through innovative lipid formulations and personalized targeting ligand designs.

The in vivo Liver-Targeted RNA Transfection Kit (SDR6002) redefines the standard for liver-targeted RNA delivery with its exceptional liver enrichment and minimal off-target expression in non-liver organs. Compared to traditional LNP technology, SDR6002 demonstrates significantly higher liver enrichment and extremely low off-target expression, enhancing the precision of RNA therapies, reducing side effects in non-target organs, and improving treatment safety and efficacy.

Compatible with Multiple RNA Types:

Suitable for delivering siRNA, gRNA, mRNA, circRNA, and more, offering broad application potential in gene therapy and research.

Tissue and Organ Targeting:

SDR6002 exhibits strong liver targeting, delivering RNA to the liver for expression via intravenous injection, improving therapeutic efficiency and minimizing impact on non-target organs.

▲ oIntravenous injection of Fluc-mRNA (10µg/mouse), 6-hour fluorescence imaging

▲ oIntravenous injection of Fluc-mRNA (10µg/mouse), 6-hour organ fluorescence distribution.

Gene Silencing Effectiveness:

● siRNA liver delivery performance surpasses GalNAc conjugate technology.

▲ Intravenous injection, siRNA liver gene silencing effect.

High Safety:

● Uses biodegradable lipid materials with excellent biocompatibility.

● Free of ethanol and other organic solvents.

● Up to 95% organ-targeted distribution, with minimal impact on other tissues or organs, ensuring reliable and effective treatment.

Why Choose in vivo NeoLNP™ Transfection Kit?

● Efficient: Maintains stable high transfection levels regardless of injection method.

● Flexible: Customizable for systemic or localized RNA delivery based on research goals.

● User-Friendly: Optimized delivery solutions enable rapid, efficient RNA encapsulation, simplifying experiments.

With the in vivo NeoLNP™ Transfection Kit, researchers can flexibly utilize multiple delivery routes to achieve precise RNA delivery, meeting unique research needs. From broad systemic applications to highly specific organ-targeted delivery, this kit is a powerful tool for cutting-edge RNA research.

Ready-to-Use LNP In Vivo Delivery Technology

The in vivo NeoLNP™ Kit stands out for its rapid and efficient RNA encapsulation capabilities. Compared to traditional methods, it requires no complex equipment, achieving efficient encapsulation through simple mixing with RNA solutions, significantly reducing preparation time. This innovation enhances RNA stability and ensures efficient transfection, offering a new transfection experience compared to traditional liposome-based nucleic acid adsorption methods.